Krewe of BOO! made a cameo appearance in the 2016 Tom Cruise film "Jack Reacher: Never Go Back." The movie was filmed throughout New Orleans including the retro diner Frostop, Lafayette Square, the old U.S. Customhouse, and Bourbon Street.

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During the climatic finale, Jack Reacher and his nemesis get caught up in the Halloween revelry of Krewe of BOO! as the parade rolls through the French Quarter before an action-packed fight scene completes the film.